PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (AP) | US Biological 040171-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (AP)

catalog :

040171-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

040171-AP

Product wo Prefix :

PLK1, CT (PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

PLK1, PLK, Serine/threonine-protein kinase PLK1, Polo-like kinase 1, Serine/threonine-protein kinase 13

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 573-603 in the C-terminal region of human PLK1, UniProt Accession #P53350; Q07832. Species Sequence Homology: mouse

Specificity :

Recognizes human PLK1.

Purity :

Purified by Protein A/G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. Labeled with Alkaline Phosphatase. Purity: Purified by Protein A/G affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 573-603 in the C-terminal region of human PLK1, UniProt Accession #P53350; Q07832. Species Sequence Homology: mouse Specificity: Recognizes human PLK1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Ree, A.H., et al., Oncogene 22(55):8952-8955 (2003). 2. Cheng, K.Y., et al., EMBO J. 22(21):5757-5768 (2003). 3. Elia, A.E., et al., Cell 115(1):83-95 (2003). 4. Lin, H.R., et al., J. Biol. Chem. 278(38):35979-35987 (2003). 5. Neef, R., et al., J. Cell Biol. 162(5):863-875 (2003).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/040171-AP_1.jpg