PKC nu (PRKD3, EPK2, PRKCN, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu)

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product summary

company name :

US Biological

product type :

antibody

product name :

PKC nu (PRKD3, EPK2, PRKCN, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu)

catalog :

040093

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

040093

Product wo Prefix :

PKC nu (PRKD3, EPK2, PRKCN, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Protein kinase C (PKC) is a family of serine- and threonine-specific protein kinases that can be activated by calcium and second messenger diacylglycerol. PKC family members phosphorylate a wide variety of protein targets and are known to be involved in diverse cellular signaling pathways. PKC also serve as major receptors for phorbol esters, a class of tumor promoters. Each member of the PKC family has a specific expression profile and is believed to play distinct roles in cells. PKC nu is one of the PKC family members. This kinase can be activated rapidly by the agonists of G protein-coupled receptors. It resides in both cytoplasm and nucleus, and its nuclear accumulation is found to be dramatically enhanced in response to its activation. This kinase can also be activated after B-cell antigen receptor (BCR) engagement, which requires intact phopholipase C gamma and the involvement of other PKC family members. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Immunofluorescence: 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

PRKD3, EPK2, PRKCN, Serine/threonine-protein kinase D3, Protein kinase C nu type, Protein kinase EPK2, nPKC-nu

Immunogen :

PKC nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361~390 amino acids from the center region of human PKC nu.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: PKC nu antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 361~390 amino acids from the center region of human PKC nu. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF IHC WB

Storage Temperature :

-20°C

Reference :

Yeaman, C., et al., Nat. Cell Biol. 6(2):106-112 (2004). Rey, O., et al., J. Biol. Chem. 278(26):23773-23785 (2003). Matthews, S.A., et al., J. Biol. Chem. 278(11):9086-9091 (2003). Bennasser, Y., et al., Virology 303(1):174-180 (2002). Bennasser, Y., et al., FASEB J. 16(6):546-554 (2002).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/29/040093_1.jpg