PITX2, NT (PITX2, ARP1, RGS, RIEG, RIEG1, Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin) (AP) | US Biological 040086-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PITX2, NT (PITX2, ARP1, RGS, RIEG, RIEG1, Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin) (AP)

catalog :

040086-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

040086-AP

Product wo Prefix :

URL USB :

www.usbio.net/antibodies/040086-AP/PITX2-NT-PITX2-ARP1-RGS-RIEG-RIEG1-Pituitary-homeobox-2-ALL1responsive-protein-ARP1-Homeobox-protein-PITX2-Pairedlike-homeodomain-transcription-factor-2-RIEG-bicoidrelated-homeobox-transcription-factor-Solurshin-AP

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a member of the RIEG/PITX homeobox family, which is in the bicoid class of homeodomain proteins. The encoded protein acts as a transcription factor and regulates procollagen lysyl hydroxylase gene expression. This protein plays a role in the terminal differentiation of somatotroph and lactotroph cell phenotypes, is involved in the development of the eye, tooth and abdominal organs, and acts as a transcriptional regulator involved in basal and hormone-regulated activity of prolactin. Mutations in this gene are associated with Axenfeld-Rieger syndrome, iridogoniodysgenesis syndrome, and sporadic cases of Peters anomaly. A similar protein in other vertebrates is involved in the determination of left-right asymmetry during development. Alternatively spliced transcript variants encoding distinct isoforms have been described. Applications:. Suitable for use in Western Blot, ELISA. Recommended Dilution:. ELISA: 1:1,000. Western Blot: 1:100-500. Storage and Stability:. Store product at 4 C. DO NOT FREEZE! Stable at 4 C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

PITX2, ARP1, RGS, RIEG, RIEG1, Pituitary homeobox 2, ALL1-responsive protein ARP1, Homeobox protein PITX2, Paired-like homeodomain transcription factor 2, RIEG bicoid-related homeobox transcription factor, Solurshin

Immunogen :

PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-71 amino acids from the N-terminal region of human PITX2.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab. Isotype: IgG. Host: rabbit. Source: human. Concentration: As reported. Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: PITX2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 41-71 amino acids from the N-terminal region of human PITX2. Specificity: Human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4 C Do Not Freeze

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). Banez, L.L., et al. J. Urol. 184(1):149-156(2010). Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506(2010). Ellinor, P.T., et al. Nat. Genet. 42(3):240-244(2010). Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

Picture 1 File Name :

usbio-images.r.worldssl.net/prodimages/47/040086-AP_1.jpg