PIK3CD (Y485) (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform, PI3-kinase p110 subunit delta, PIK3CD) (APC) | US Biological 040042-APC product information

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product summary

company name :

US Biological

product type :

antibody

product name :

PIK3CD (Y485) (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform, PI3-kinase p110 subunit delta, PIK3CD) (APC)

catalog :

040042-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

040042-APC

Product wo Prefix :

PIK3CD (Y485) (Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform, PI3-kinase p110 subunit delta, PIK3CD) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

PI3-Kinases (PI3-Ks) are a family of lipid kinases that are implicated in signal transduction. PI3-K consists of two subunits; p85 and p110. The p85 subunit localize PI3-K activity to the plasma membrane while the p110 subunit contains the catalytic domain of PI3-K. Four isoforms of p110 has been found; the alpha, beta, gamma, and the delta subunit. The delta isoform is predominantly expressed in leukocytes and has been shown to interact with p85 and GTP-bound Ras via its SH2/SH3 domain. Applications: Suitable for use in Immunohistochemistry, FLISA Recommended Dilution: FLISA: 1:1,000 Immunohistochemistry: 1:10-50 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

Phosphatidylinositol-4,5-bisphosphate 3-kinase catalytic subunit, delta isoform, PI3-kinase p110 subunit delta, PIK3CD

Immunogen :

PIK3CD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y485 of human PI3KCD.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: PIK3CD antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide corresponding to amino acid residues surrounding Y485 of human PI3KCD. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL IHC

Storage Temperature :

4°C Do Not Freeze

Reference :

Vanhaesebroeck, B., et al., Proc. Natl. Acad. Sci. U.S.A. 94(9):4330-4335 (1997). Chantry, D., et al., J. Biol. Chem. 272(31):19236-19241 (1997).