PI3KCG, NT (Phosphatidylinositol 3-kinase, catalytic, gamma polypeptide, Phosphatidylinositol 3-kinase catalytic 110-kD gamma) (AP) | US Biological 039998-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

PI3KCG, NT (Phosphatidylinositol 3-kinase, catalytic, gamma polypeptide, Phosphatidylinositol 3-kinase catalytic 110-kD gamma) (AP)

catalog :

039998-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

039998-AP

Product wo Prefix :

PI3KCG, NT (Phosphatidylinositol 3-kinase, catalytic, gamma polypeptide, Phosphatidylinositol 3-kinase catalytic 110-kD gamma) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

PI3KCG belongs to the pi3/pi4-kinase family of proteins. This protein is an enzyme that phosphorylates phosphoinositides on the 3-hydroxyl group of the inositol ring. It is an important modulator of extracellular signals, including those elicited by E-cadherin-mediated cell-cell adhesion, which plays an important role in maintenance of the structural and functional integrity of epithelia. In addition to its role in promoting assembly of adherens junctions, the protein is thought to play a pivotal role in the regulation of cytotoxicity in NK cells. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Alternate Name :

Phosphatidylinositol 3-kinase, catalytic, gamma polypeptide, Phosphatidylinositol 3-kinase catalytic 110-kD gamma

Immunogen :

PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PI3KCG.

Specificity :

Human, mouse

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: PI3KCG antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the N-terminal region of human PI3KCG. Specificity: Human, mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Resendiz, J.C., et al., Mol. Pharmacol. 63(3):639-645 (2003). Francois, F., et al., J. Virol. 77(4):2539-2549 (2003). Chandrasekar, N., et al., Oncogene 22(3):392-400 (2003). Ishibashi, Y., et al., Cell. Microbiol. 4(12):825-833 (2002). Semba, S., et al., Clin. Cancer Res. 8(12):3824-3831 (2002).