antibody

PFKP, CT (PFKP, PFKF, 6-phosphofructokinase type C, 6-phosphofructokinase, platelet type, Phosphofructo-1-kinase isozyme C, Phosphofructokinase 1, Phosphohexokinase) (APC)

039903-APC

200 ul

polyclonal

domestic rabbit

APC

PFKP, CT (PFKP, PFKF, 6-phosphofructokinase type C, 6-phosphofructokinase, platelet type, Phosphofructo-1-kinase isozyme C, Phosphofructokinase 1, Phosphohexokinase) (APC)

rabbit

Pab

APC

Antibodies

200 ul

IgG

Protein kinases are enzymes that transfer a phosphate group from a phosphate donor, generally the g phosphate of ATP, onto an acceptor amino acid in a substrate protein. By this basic mechanism, protein kinases mediate most of the signal transduction in eukaryotic cells, regulating cellular metabolism, transcription, cell cycle progression, cytoskeletal rearrangement and cell movement, apoptosis, and differentiation. With more than 500 gene products, the protein kinase family is one of the largest families of proteins in eukaryotes. The family has been classified in 8 major groups based on sequence comparison of their tyrosine (PTK) or serine/threonine (STK) kinase catalytic domains. The AGC kinase group consists of 63 kinases including the cyclic nucleotide-regulated protein kinase (PKA & PKG) family, the diacylglycerol-activated/phospholipid-dependent protein kinase C (PKC) family, the related to PKA and PKC (RAC/Akt) protein kinase family, the kinases that phosphorylate G protein-coupled receptors family (ARK), and the kinases that phosphorylate ribosomal protein S6 family (RSK). Applications: Suitable for use in Western Blot, Immunohistochemistry, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

PFKP, PFKF, 6-phosphofructokinase type C, 6-phosphofructokinase, platelet type, Phosphofructo-1-kinase isozyme C, Phosphofructokinase 1, Phosphohexokinase

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 754-784 in the C-terminal region of human PFKP, UniProt Accession #Q01813.

Recognizes human PFKP.

Purified by Protein A/G affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A/G affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 754-784 in the C-terminal region of human PFKP, UniProt Accession #Q01813. Specificity: Recognizes human PFKP. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

FL IHC WB

4°C Do Not Freeze

1. Adam, G.C., et al., Mol. Cell Proteomics 1(10):828-835 (2002). 2. Bonaldo, M.F., et al., Genome Res. 6(9):791-806 (1996). 3. Morrison, N., et al., Hum. Genet. 89(1):105-106 (1992). 4. Simpson, C.J., et al., Biochem. Biophys. Res. Commun. 180(1):197-203 (1991). 5. Nakajima, H., et al., FEBS Lett. 223(1):113-116 (1987).

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