PDGFRA, ID (PDGF-R-alpha, CD140a antigen, Alpha platelet-derived growth factor receptor)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

PDGFRA, ID (PDGF-R-alpha, CD140a antigen, Alpha platelet-derived growth factor receptor)

catalog :

039818

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

039818

Product wo Prefix :

PDGFRA, ID (PDGF-R-alpha, CD140a antigen, Alpha platelet-derived growth factor receptor)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

PDGFRA is a cell surface tyrosine kinase receptor for members of the platelet-derived growth factor family. These growth factors are mitogens for cells of mesenchymal origin. The identity of the growth factor bound to a receptor monomer determines whether the functional receptor is a homodimer or a heterodimer, composed of both platelet-derived growth factor receptor alpha and beta polypeptides. Studies in knockout mice, where homozygosity is lethal, indicate that the alpha form of the platelet-derived growth factor receptor is particularly important for kidney development since mice heterozygous for the receptor exhibit defective kidney phenotypes. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-100 Flow Cytometry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

PDGF-R-alpha, CD140a antigen, Alpha platelet-derived growth factor receptor

Immunogen :

PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PDGFRA.

Specificity :

Recognizes human PDGFRA

Purity :

Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. Immunogen: PDGFRA antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the center region of human PDGFRA. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

1. Wilczynski, S.P., et al., Hum. Pathol. 36(3):242-249 (2005). 2. Hiwatari, M., et al., Leukemia 19(3):476-477 (2005). 3. Debiec-Rychter, M., et al., Gastroenterology 128(2):270-279 (2005). 4. Sakurai, S., et al., Hum. Pathol. 35(10):1223-1230 (2004). 5. Subramanian, S., et al., Oncogene 23(47):7780-7790 (2004).