NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (APC) | US Biological 039128-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (APC)

catalog :

039128-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

039128-APC

Product wo Prefix :

NR3C1, ID (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, FLISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Alternate Name :

NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 236-262 in the central region of human NR3C1, UniProt Accession #NP_000167.1; P04150; P59667.

Specificity :

Recognizes human NR3C1. Species Crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 236-262 in the central region of human NR3C1, UniProt Accession #NP_000167.1; P04150; P59667. Specificity: Recognizes human NR3C1. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL IF IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Bosker, F.J., et al. Mol. Psychiatry (2010) 2. Inkster, B., et al. Neuroimage (2010) 3. Geelhoed, M.J., et al. BMC Med. Genet. 11, 39 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/28/039128-APC_1.png