NR3C1, CT (Nuclear receptor subfamily 3 group C member 1, Glucocorticoid receptor, GR,GRL, NR3C1) (AP) | US Biological 039127-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NR3C1, CT (Nuclear receptor subfamily 3 group C member 1, Glucocorticoid receptor, GR,GRL, NR3C1) (AP)

catalog :

039127-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

039127-AP

Product wo Prefix :

NR3C1, CT (Nuclear receptor subfamily 3 group C member 1, Glucocorticoid receptor, GR,GRL, NR3C1) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

NR3C1 is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

Nuclear receptor subfamily 3 group C member 1, Glucocorticoid receptor, GR,GRL, NR3C1

Immunogen :

NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 712-742 from the C-terminal region of human NR3C1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between amino acids 712-742 from the C-terminal region of human NR3C1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Geelhoed, M.J., et al. BMC Med. Genet. 11, 39 (2010) Szilagyi, K., et al. Neuro Endocrinol. Lett. 30(5):629-636(2009) Tian, S., et al. Biochem. J. 367 (PT 3), 907-911 (2002) Itoh, M., et al. Mol. Endocrinol. 16(10):2382-2392(2002) Wang, Z., et al. J. Biol. Chem. 277(29):26573-26580(2002)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/2/039127-AP_1.jpg