NR3C1, CT (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (AP) | US Biological 039126-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NR3C1, CT (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (AP)

catalog :

039126-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

039126-AP

Product wo Prefix :

NR3C1, CT (NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a receptor for glucocorticoids that can act as both a transcription factor and as a regulator of other transcription factors. This protein can also be found in heteromeric cytoplasmic complexes along with heat shock factors and immunophilins. The protein is typically found in the cytoplasm until it binds a ligand, which induces transport into the nucleus. Mutations in this gene are a cause of glucocorticoid resistance, or cortisol, resistance. Alternate splicing, the use of at least three different promoters, and alternate translation initiation sites result in several transcript variants encoding the same protein or different isoforms, but the full-length nature of some variants has not been determined. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

NR3C1, GRL, Glucocorticoid receptor, Nuclear receptor subfamily 3 group C member 1

Immunogen :

NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-588 amino acids from the C-terminal region of human NR3C1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: NR3C1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 560-588 amino acids from the C-terminal region of human NR3C1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Seitz, T., et al. J. Mol. Biol. 403(4):562-577(2010) Wang, W., et al. Nucleic Acids Res. (2010) In press : Sarzynski, M.A., et al. Int J Obes (Lond) (2010) In press : Desrivieres, S., et al. Addict Biol (2010) In press : van Oosten, M.J., et al. Arthritis Res. Ther. 12 (4), R159 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/46/039126-AP_1.jpg