NOX4, NT (NOX4, RENOX, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase) (AP) | US Biological 039072-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NOX4, NT (NOX4, RENOX, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase) (AP)

catalog :

039072-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

039072-AP

Product wo Prefix :

NOX4, NT (NOX4, RENOX, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a member of the NOX-family of enzymes that functions as the catalytic subunit the NADPH oxidase complex. The encoded protein is localized to non-phagocytic cells where it acts as an oxygen sensor and catalyzes the reduction of molecular oxygen to various reactive oxygen species (ROS). The ROS generated by this protein have been implicated in numerous biological functions including signal transduction, cell differentiation and tumor cell growth. A pseudogene has been identified on the other arm of chromosome 11. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

NOX4, RENOX, NADPH oxidase 4, Kidney oxidase-1, Kidney superoxide-producing NADPH oxidase, Renal NAD(P)H-oxidase

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 124-153 in the N-terminal region of human NOX4, UniProt Accession #Q9NPH5.

Specificity :

Recognizes human NOX4.

Purity :

Purified by Protein A and peptide affinity chromatography

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 124-153 in the N-terminal region of human NOX4, UniProt Accession #Q9NPH5. Specificity: Recognizes human NOX4. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253 (2010). 2. Salmeen, A., et al. Oncogene 29(31):4473-4484 (2010). 3. Wu, R.F., et al. Mol. Cell. Biol. 30(14):3553-3568 (2010). 4. Diebold, I., et al. Mol. Biol. Cell 21(12):2087-2096 (2010). 5. Manea, A., et al. Biochem. Biophys. Res. Commun. 396(4):901-907 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/43/039072-AP_1.jpg