NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9) (AP) | US Biological 038941-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9) (AP)

catalog :

038941-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

038941-AP

Product wo Prefix :

NFKBIB, CT (NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

NFKB1 (MIM 164011) or NFKB2 (MIM 164012) is bound to REL (MIM 164910), RELA (MIM 164014), or RELB (MIM 604758) to form the NFKB complex. The NFKB complex is inhibited by I-kappa-B proteins (NFKBIA, MIM 164008, or NFKBIB), which inactivate NF-kappa-B by trapping it in the cytoplasm. Phosphorylation of serine residues on the I-kappa-B proteins by kinases (IKBKA, MIM 600664 or IKBKB, MIM 603258) marks them for destruction via the ubiquitination pathway, thereby allowing activation of the NF-kappa-B complex. Activated NFKB complex translocates into the nucleus and binds DNA at kappa-B-binding motifs such as 5-prime GGGRNNYYCC 3-prime or 5-prime HGGARNYYCC 3-prime (where H is A, C, or T; R is an A or G purine; and Y is a C or T pyrimidine). Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

NFKBIB, IKBB, TRIP9, NF-kappa-B inhibitor beta, I-kappa-B-beta, Thyroid receptor-interacting protein 9

Immunogen :

NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the C-terminal region of human NFKBIB.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: NFKBIB antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 325-355 amino acids from the C-terminal region of human NFKBIB. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Potter, C., et al. Ann. Rheum. Dis. 69(7):1315-1320(2010) Segat, L., et al. Vaccine 28(10):2201-2206(2010) McGeachie, M., et al. Circulation 120(24):2448-2454(2009) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/5/038941-AP_1.jpg