antibody

NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, EBP-1, Nuclear factor of kappa light polypeptide gene enhancer in B Cells 1, Nuclear factor NF-kappa-B p50 subunit) (AP)

038937-AP

200 ul

polyclonal

domestic rabbit

AP

NFKB, p105, CT (S933) (NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, EBP-1, Nuclear factor of kappa light polypeptide gene enhancer in B Cells 1, Nuclear factor NF-kappa-B p50 subunit) (AP)

rabbit

Pab

AP

Antibodies

200 ul

IgG

This gene encodes a 105 kD protein which can undergo cotranslational processing by the 26S proteasome to produce a 50 kD protein. The 105 kD protein is a Rel protein-specific transcription inhibitor and the 50 kD protein is a DNA binding subunit of the NF-kappa-B (NFKB) protein complex. NFKB is a transcription regulator that is activated by various intra- and extra-cellular stimuli such as cytokines, oxidant-free radicals, ultraviolet irradiation, and bacterial or viral products. Activated NFKB translocates into the nucleus and stimulates the expression of genes involved in a wide variety of biological functions. Inappropriate activation of NFKB has been associated with a number of inflammatory diseases while persistent inhibition of NFKB leads to inappropriate immune cell development or delayed cell growth. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

NFKB1, Nuclear factor NF-kappa-B p105 subunit, DNA-binding factor KBF1, EBP-1, Nuclear factor of kappa light polypeptide gene enhancer in B-cells 1, Nuclear factor NF-kappa-B p50 subunit

NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-938 amino acids from the C-terminal region of human NFKB(p105).

Human

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: NFKB(p105) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 912-938 amino acids from the C-terminal region of human NFKB(p105). Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E WB

4°C Do Not Freeze

Beshir, A.B., et al. Cancer Lett. 299(2):137-149(2010) Song, C., et al. Virology 407(2):268-280(2010) Gonsalves, C., et al. J. Immunol. 185(10):6253-6264(2010) Kingeter, L.M., et al. J. Immunol. 185(8):4520-4524(2010) Clarke, D.L., et al. J. Biol. Chem. 285(38):29101-29110(2010)

https://usbio-images.r.worldssl.net/prodimages/36/038937-AP_1.jpg