MMP2, ID (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MMP2, ID (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX)

catalog :

038507

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

038507

Product wo Prefix :

MMP2, ID (MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Proteins of the matrix metalloproteinase (MMP) family are involved in the breakdown of extracellular matrix in normal physiological processes, such as embryonic development, reproduction, and tissue remodeling, as well as in disease processes, such as arthritis and metastasis. Most MMP's are secreted as inactive proproteins which are activated when cleaved by extracellular proteinases. This gene encodes an enzyme which degrades type IV collagen, the major structural component of basement membranes. The enzyme plays a role in endometrial menstrual breakdown, regulation of vascularization and the inflammatory response. Mutations in this gene have been associated with Winchester syndrome and Nodulosis-Arthropathy-Osteolysis (NAO) syndrome. Two transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in ELISA and Western Blot. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

MMP2, CLG4A, 72kD type IV collagenase, 72kD gelatinase, Gelatinase A, Matrix metalloproteinase-2, TBE-1, PEX

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 303-331 in the central region of human MMP2, UniProt Accession #NP_004521.1; P08253. Species sequence homology: chicken, mouse, rabbit and rat.

Specificity :

Recognizes human MMP2.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 303-331 in the central region of human MMP2, UniProt Accession #NP_004521.1; P08253. Species sequence homology: chicken, mouse, rabbit and rat. Specificity: Recognizes human MMP2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Beshir, A.B., et al. Cancer Lett. 299(2):137-149(2010) 2. Alakus, H., et al. World J Surg 34(12):2853-2859(2010) 3. Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) 4. Nikopensius, T., et al. Birth Defects Res. Part A Clin. Mol. Teratol. 88(9):748-756(2010) 5. Mossbock, G., et al. Mol. Vis. 16, 1764-1770 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/0/038507_1.png