MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

catalog :

038468

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

038468

Product wo Prefix :

MLH1, ID (MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene was identified as a locus frequently mutated in hereditary nonpolyposis colon cancer (HNPCC). It is a human homolog of the E. coli DNA mismatch repair gene mutL, consistent with the characteristic alterations in microsatellite sequences (RER+phenotype) found in HNPCC. Alternative splicing results in multiple transcript variants encoding distinct isoforms. Additional transcript variants have been described, but their full-length natures have not been determined. Applications: Suitable for use in Western Blot, Flow Cytometry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Flow Cytometry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

MLH1, COCA2, DNA mismatch repair protein Mlh1, MutL protein homolog 1

Immunogen :

MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the Central region of human MLH1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: MLH1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 459-488 amino acids from the Central region of human MLH1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC WB

Storage Temperature :

-20°C

Reference :

Ling, Z.Q., et al. Cancer Lett. 297(2):244-251(2010) Qi, Y., et al. J. Biol. Chem. 285(43):33010-33017(2010) Borras, E., et al. Cancer Res. 70(19):7379-7391(2010) Mangoni, M., et al. Int. J. Radiat. Oncol. Biol. Phys. (2010) In press : Ho-Pun-Cheung, A., et al. Pharmacogenomics J. (2010) In press :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/32/038468_1.jpg