MDM4, ID (MDM4, MDMX, Protein Mdm4, Protein Mdmx, Double minute 4 protein, Mdm2-like p53-binding protein, p53-binding protein Mdm4) (APC) | US Biological 038303-APC product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

MDM4, ID (MDM4, MDMX, Protein Mdm4, Protein Mdmx, Double minute 4 protein, Mdm2-like p53-binding protein, p53-binding protein Mdm4) (APC)

catalog :

038303-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

038303-APC

Product wo Prefix :

MDM4, ID (MDM4, MDMX, Protein Mdm4, Protein Mdmx, Double minute 4 protein, Mdm2-like p53-binding protein, p53-binding protein Mdm4) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The human MDM4 gene, which plays a role in apoptosis, encodes a 490-amino acid protein containing a RING finger domain and a putative nuclear localization signal. The MDM4 putative nuclear localization signal, which all Mdm proteins contain, is located in the C-terminal region of the protein. The mRNA is expressed at a high level in thymus and at lower levels in all other tissues tested. MDM4 protein produced by in vitro translation interacts with p53 via a binding domain located in the N-terminal region of the MDM4 protein. MDM4 shows significant structural similarity to p53-binding protein MDM2. Two transcript variants, one protein-coding and the other likely not to be protein-coding, have been found for this gene. Applications: Suitable for use in Western Blot, FLISA Recommended Dilution: FLISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

MDM4, MDMX, Protein Mdm4, Protein Mdmx, Double minute 4 protein, Mdm2-like p53-binding protein, p53-binding protein Mdm4

Immunogen :

MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of human MDM4.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A affinity chromatography. Immunogen: MDM4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 127-157 amino acids from the Central region of human MDM4. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FL WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Xu, N., et al. Biochem. Biophys. Res. Commun. 401(3):417-421(2010) Sarkari, F., et al. J. Mol. Biol. 402(5):825-837(2010) Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Fang, S., et al. PLoS ONE 5 (5), E10813 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/43/038303-APC_1.jpg