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product summary
company name :
US Biological
product type :
antibody
product name :
MCL1, ID (MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT)
catalog :
038276
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
038276
Product wo Prefix :
MCL1, ID (MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Applications:
Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications not tested.
Recommended Dilutions:
Western Blot: 1:1000
Immunohistochemistry (FFPE): 1:10-50
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT
Immunogen :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 217-245 in the central region of human MCL1, UniProt Accession #Q07820; NP_877495.1; NP_068779.1; Q9Z1P3. Species Sequence Homology: rat
Specificity :
Recognizes human MCL1.
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As Reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As Reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A affinity chromatography.
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 217-245 in the central region of human MCL1, UniProt Accession #Q07820; NP_877495.1; NP_068779.1; Q9Z1P3. Species Sequence Homology: rat
Specificity: Recognizes human MCL1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
-20°C
Reference :
1. Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 3. Kim, J.H., et al. FEBS Lett. 583(17):2758-2764(2009) 4. Maurer, U., et al. Mol. Cell 21(6):749-760(2006) 5. Domina, A.M., et al. Oncogene 23(31):5301-5315(2004)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/17/038276_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
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