This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
MCL1, ID (MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT) (AP)
catalog :
038276-AP
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
AP
reactivity :
human
product information
Catalog Number :
038276-AP
Product wo Prefix :
MCL1, ID (MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT) (AP)
Host :
rabbit
Product Type :
Pab
Conjugate :
AP
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
This gene encodes an anti-apoptotic protein, which is a member of the Bcl-2 family. Alternative splicing results in multiple transcript variants. The longest gene product (isoform 1) enhances cell survival by inhibiting apoptosis while the alternatively spliced shorter gene products (isoform 2 and isoform 3) promote apoptosis and are death-inducing.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and Stability:
Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
Alternate Name :
MCL1, BCL2L3, Induced myeloid leukemia cell differentiation protein Mcl-1, Bcl-2-like protein 3, Bcl-2-related protein EAT/mcl1, mcl1/EAT
Immunogen :
KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 217-245 in the central region of human MCL1, UniProt Accession #Q07820; NP_877495.1; NP_068779.1; Q9Z1P3. Species Sequence Homology: rat
Specificity :
Recognizes human MCL1.
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Concentration :
As Reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As Reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).
Purity: Purified by Protein A affinity chromatography.
Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 217-245 in the central region of human MCL1, UniProt Accession #Q07820; NP_877495.1; NP_068779.1; Q9Z1P3. Species Sequence Homology: rat
Specificity: Recognizes human MCL1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
4°C Do Not Freeze
Reference :
1. Shimada, M., et al. Hum. Genet. 128(4):433-441(2010) 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 3. Kim, J.H., et al. FEBS Lett. 583(17):2758-2764(2009) 4. Maurer, U., et al. Mol. Cell 21(6):749-760(2006) 5. Domina, A.M., et al. Oncogene 23(31):5301-5315(2004)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/22/038276-AP_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
questions and comments