LIMK1, phosphorylated (Thr508) (LIMK1, LIMK, LIM domain kinase 1) (AP) | US Biological 037787-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

LIMK1, phosphorylated (Thr508) (LIMK1, LIMK, LIM domain kinase 1) (AP)

catalog :

037787-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

037787-AP

Product wo Prefix :

LIMK1, phosphorylated (Thr508) (LIMK1, LIMK, LIM domain kinase 1) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

There are approximately 40 known eukaryotic LIM proteins, so named for the LIM domains they contain. LIM domains are highly conserved cysteine-rich structures containing 2 zinc fingers. Although zinc fingers usually function by binding to DNA or RNA, the LIM motif probably mediates protein-protein interactions. LIM kinase-1 and LIM kinase-2 belong to a small subfamily with a unique combination of 2 N-terminal LIM motifs and a C-terminal protein kinase domain. LIMK1 is likely to be a component of an intracellular signaling pathway and may be involved in brain development. LIMK1 hemizygosity is implicated in the impaired visuospatial constructive cognition of Williams syndrome. [provided by RefSeq]. Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Dot blot 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

LIMK1, LIMK, LIM domain kinase 1

Immunogen :

Phospho-LIMK1 (Thr508) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Thr508 of human LIMK1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: Phospho-LIMK1 (Thr508) antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected surrounding Thr508 of human LIMK1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB E

Storage Temperature :

4°C Do Not Freeze

Reference :

Roder, C., et al. Childs Nerv Syst (2010) In press : Borensztajn, K., et al. Thromb. Res. 125 (6), E323-E328 (2010) : Saxena, M., et al. J Cancer Res Ther 6(2):167-171(2010) Mishima, T., et al. Biochem. Biophys. Res. Commun. 392(4):577-581(2010) Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/0/037787-AP_1.jpg