LEF1, NT (LEF1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

LEF1, NT (LEF1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha)

catalog :

037732

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

037732

Product wo Prefix :

LEF1, NT (LEF1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a transcription factor belonging to a family of proteins that share homology with the high mobility group protein-1. The protein encoded by this gene can bind to a functionally important site in the T-cell receptor-alpha enhancer, thereby conferring maximal enhancer activity. This transcription factor is involved in the Wnt signaling pathway, and it may function in hair cell differentiation and follicle morphogenesis. Mutations in this gene have been found in somatic sebaceous tumors. This gene has also been linked to other cancers, including androgen-independent prostate cancer. Alternative splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot, ELISA and Immunofluorescence. Other applications not tested. Recommended Dilutions: Western Blot: 1:1000 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receeipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

LEF1, Lymphoid enhancer-binding factor 1, T cell-specific transcription factor 1-alpha

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 10-37 in the N-terminal region of human LEF1, UniProt Accession #NP_057353.1; Q9UJU2; Q9QXN1; P27782. Species Sequence Homology: mouse and rat

Specificity :

Recognizes human LEF1.

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 10-37 in the N-terminal region of human LEF1, UniProt Accession #NP_057353.1; Q9UJU2; Q9QXN1; P27782. Species Sequence Homology: mouse and rat Specificity: Recognizes human LEF1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF WB

Storage Temperature :

-20°C

Reference :

1. Gutierrez, A. Jr., et al. Blood 116(16):2975-2983 (2010). 2. Kalsi, G., et al. Hum. Mol. Genet. 19(12):2497-2506 (2010). 3. Chen, Q.Y., et al. J. Immunol. 184(9):5047-5054 (2010). 4. Beagle, B., et al. PLoS ONE 5 (7), E11821 (2010). 5. Jugessur, A., et al. PLoS ONE 5 (7), E11493 (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/40/037732_1.jpg