L1CAM, CT (L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, CD171) (AP) | US Biological 037654-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

L1CAM, CT (L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, CD171) (AP)

catalog :

037654-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

037654-AP

Product wo Prefix :

L1CAM, CT (L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, CD171) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

L1CAM is an axonal glycoprotein belonging to the immunoglobulin supergene family. The ectodomain, consisting of several immunoglobulin-like domains and fibronectin-like repeats (type III), is linked via a single transmembrane sequence to a conserved cytoplasmic domain. This cell adhesion molecule plays an important role in nervous system development, including neuronal migration and differentiation. Mutations in the gene cause three X-linked neurological syndromes known by the acronym CRASH (corpus callosum hypoplasia, retardation, aphasia, spastic paraplegia and hydrocephalus). Alternative splicing of a neuron-specific exon is thought to be functionally relevant. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Alternate Name :

L1CAM, CAML1, MIC5, Neural cell adhesion molecule L1, CD171

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1154-1182 in the C-terminal region of human L1CAM. Species sequence homology: rat

Specificity :

Recognizes human L1CAM, CT. Species crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 1154-1182 in the C-terminal region of human L1CAM. Species sequence homology: rat Specificity: Recognizes human L1CAM, CT. Species crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Schafer, M.K., et al. FEBS Lett. 584(21):4475-4480(2010) 2. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) 3. Bertolin, C., et al. J. Neurol. Sci. 294 (1-2), 124-126 (2010) :4. Schafer, M.K., et al. Cell. Mol. Life Sci. 67(14):2425-2437(2010) 5. Gavert, N., et al. J. Cell. Sci. 123 (PT 12), 2135-2143 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/13/037654-AP_1.jpg