KDR, phosphorylated (Y1175) (KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1)

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product summary

company name :

US Biological

product type :

antibody

product name :

KDR, phosphorylated (Y1175) (KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1)

catalog :

037376

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

antigen modification :

phosphorylated

reactivity :

human

product information

Catalog Number :

037376

Product wo Prefix :

KDR, phosphorylated (Y1175) (KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1)

Host :

rabbit

Product Type :

Pab

Antigen Modification :

phosphorylated

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Vascular endothelial growth factor (VEGF) is a major growth factor for endothelial cells. This gene encodes one of the two receptors of the VEGF. This receptor, known as kinase insert domain receptor, is a type III receptor tyrosine kinase. It functions as the main mediator of VEGF-induced endothelial proliferation, survival, migration, tubular morphogenesis and sprouting. The signalling and trafficking of this receptor are regulated by multiple factors, including Rab GTPase, P2Y purine nucleotide receptor, integrin alphaVbeta3, T-cell protein tyrosine phosphatase, etc. Applications: Suitable for use in Dot Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Dot blot 1:500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

KDR, FLK1, VEGFR2, Vascular endothelial growth factor receptor 2, Fetal liver kinase 1, Kinase insert domain receptor, Protein-tyrosine kinase receptor flk-1

Immunogen :

Phospho-KDR-Y1175 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 1160~1190 amino acids surrounding Y1175 of human KDR.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: Phospho-KDR-Y1175 antibody is generated from rabbits immunized with a KLH conjugated synthetic phosphopeptide between 1160~1190 amino acids surrounding Y1175 of human KDR. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

DB E

Storage Temperature :

-20°C

Reference :

Huang, D., et al. Cancer Res. 70(3):1053-1062(2010) Sentilhes, L., et al. J. Neuropathol. Exp. Neurol. 69(2):111-128(2010) Lamalice, L., et al. J. Biol. Chem. 281(45):34009-34020(2006)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/18/037376_1.jpg