This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
IRF4, ID (IRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, NF-EM5)
catalog :
037104
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
037104
Product wo Prefix :
IRF4, ID (IRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, NF-EM5)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
The protein encoded by this gene belongs to the IRF (interferon regulatory factor) family of transcription factors, characterized by an unique tryptophan pentad repeat DNA-binding domain. The IRFs are important in the regulation of interferons in response to infection by virus, and in the regulation of interferon-inducible genes. This family member is lymphocyte specific and negatively regulates Toll-like-receptor (TLR) signaling that is central to the activation of innate and adaptive immune systems. A chromosomal translocation involving this gene and the IgH locus, t(6;14)(p25;q32), may be a cause of multiple myeloma. Alternatively spliced transcript variants have been found for this gene. Applications: Suitable for use in Western Blot, Flow Cytometry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-100 Flow Cytometry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
IRF4, MUM1, Interferon regulatory factor 4, Lymphocyte-specific interferon regulatory factor, Multiple myeloma oncogene 1, NF-EM5
Immunogen :
IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4.
Specificity :
Human
Purity :
Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. Immunogen: IRF4 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 171-199 amino acids from the Central region of human IRF4. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC WB
Storage Temperature :
-20°C
Reference :
Ucisik-Akkaya, E., et al. Mol. Hum. Reprod. 16(10):770-777(2010) Staudt, V., et al. Immunity 33(2):192-202(2010) Newton-Bishop, J.A., et al. Cancer Epidemiol. Biomarkers Prev. 19(8):2043-2054(2010) Duffy, D.L., et al. Am. J. Hum. Genet. 87(1):6-16(2010) Eriksson, N., et al. PLoS Genet. 6 (6), E1000993 (2010) :
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/13/037104_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
service@usbio.net
https://www.usbio.net
800-520-3011
headquarters: USA
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