IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha) (AP) | US Biological 036976-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha) (AP)

catalog :

036976-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

036976-AP

Product wo Prefix :

IL15RA, ID (IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a cytokine receptor that specifically binds interleukin 15 (IL15) with high affinity. The receptors of IL15 and IL2 share two subunits, IL2R beta and IL2R gamma. This forms the basis of many overlapping biological activities of IL15 and IL2. The protein encoded by this gene is structurally related to IL2R alpha, an additional IL2-specific alpha subunit necessary for high affinity IL2 binding. Unlike IL2RA, IL15RA is capable of binding IL15 with high affinity independent of other subunits, which suggests distinct roles between IL15 and IL2. This receptor is reported to enhance cell proliferation and expression of apoptosis inhibitor BCL2L1/BCL2-XL and BCL2. Multiple alternatively spliced transcript variants of this gene have been reported. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilutions: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

IL15RA, Interleukin-15 receptor subunit alpha, CD215, Soluble interleukin-15 receptor subunit alpha

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 79-106 in the the Central region of human IL15RA.

Specificity :

Recognizes human IL15RA.

Purity :

Purified by Protein A and peptide affinity chromatography

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 79-106 in the the Central region of human IL15RA. Specificity: Recognizes human IL15RA. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Wu, Z., et al. J Mol Cell Biol 2(4):217-222(2010). 2. Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010). 3. Schuurhof, A., et al. Pediatr. Pulmonol. 45(6):608-613(2010). 4. Yokoyama, K., et al. Nephron Clin Pract 115 (4), C237-C243 (2010). 5. Bergamaschi, C., et al. J. Immunol. 183(5):3064-3072(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/44/036976-AP_1.jpg