IL12B, CT (IL12B, NKSF2, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2) (AP) | US Biological 036971-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

IL12B, CT (IL12B, NKSF2, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2) (AP)

catalog :

036971-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

036971-AP

Product wo Prefix :

IL12B, CT (IL12B, NKSF2, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

IL12B is a subunit of interleukin 12, a cytokine that acts on T and natural killer cells, and has a broad array of biological activities. Interleukin 12 is a disulfide-linked heterodimer composed of the 40 kD cytokine receptor like subunit encoded by this gene, and a 35 kD subunit encoded by IL12A. This cytokine is expressed by activated macrophages that serve as an essential inducer of Th1 cells development. This cytokine has been found to be important for sustaining a sufficient number of memory/effector Th1 cells to mediate long-term protection to an intracellular pathogen. Overexpression of this gene was observed in the central nervous system of patients with multiple sclerosis (MS), suggesting a role of this cytokine in the pathogenesis of the disease. The promoter polymorphism of this gene has been reported to be associated with the severity of atopic and non-atopic asthma in children. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:50-100 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

IL12B, NKSF2, Interleukin-12 subunit beta, Cytotoxic lymphocyte maturation factor 40kD subunit, IL-12 subunit p40, NK cell stimulatory factor chain 2

Immunogen :

IL12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human IL12B.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: IL12B antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 271-298 amino acids from the C-terminal region of human IL12B. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Romero, R., et al. Am. J. Obstet. Gynecol. 203 (4), 361 (2010) : Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010) Miteva, L.D., et al. Rheumatol. Int. (2010) In press : de Heens, G.L., et al. J. Clin. Periodontol. 37(2):129-136(2010) Sobti, R.C., et al. Folia Biol. (Praha) 56(3):110-115(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/14/036971-AP_1.jpg