IKZF3, ID (IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

IKZF3, ID (IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3)

catalog :

036968

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

036968

Product wo Prefix :

IKZF3, ID (IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a member of the Ikaros family of zinc-finger proteins. Three members of this protein family (Ikaros, Aiolos and Helios) are hematopoietic-specific transcription factors involved in the regulation of lymphocyte development. This gene product is a transcription factor that is important in the regulation of B lymphocyte proliferation and differentiation. Both Ikaros and Aiolos can participate in chromatin remodeling. Regulation of gene expression in B lymphocytes by Aiolos is complex as it appears to require the sequential formation of Ikaros homodimers, Ikaros/Aiolos heterodimers, and Aiolos homodimers. At least six alternative transcripts encoding different isoforms have been described. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Alternate Name :

IKZF3, ZNFN1A3, Zinc finger protein Aiolos, Ikaros family zinc finger protein 3

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 76-103 in the central region of human IKZF3. Species sequence homology: bovine

Specificity :

Recognizes human IKZF3. Species Crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 76-103 in the central region of human IKZF3. Species sequence homology: bovine Specificity: Recognizes human IKZF3. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Billot, K., et al. Leuk. Res. 34(3):289-293(2010) 2. Hirschfield, G.M., et al. N. Engl. J. Med. 360(24):2544-2555(2009) 3. Mavaddat, N., et al. Cancer Epidemiol. Biomarkers Prev. 18(1):255-259(2009) 4. Vieira, A.R., et al. Genet. Med. 10(9):668-674(2008)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/46/036968_1.jpg