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product summary
company name :
US Biological
product type :
antibody
product name :
HDAC3, CT (HDAC3, Histone deacetylase 3, RPD3-2, SMAP45)
catalog :
036478
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
036478
Product wo Prefix :
HDAC3, CT (HDAC3, Histone deacetylase 3, RPD3-2, SMAP45)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
Histones play a critical role in transcriptional regulation, cell cycle progression, and developmental events. Histone acetylation/deacetylation alters chromosome structure and affects transcription factor access to DNA. The protein encoded by this gene belongs to the histone deacetylase/acuc/apha family. It has histone deacetylase activity and represses transcription when tethered to a promoter. It may participate in the regulation of transcription through its binding with the zinc-finger transcription factor YY1. This protein can also down-regulate p53 function and thus modulate cell growth and apoptosis. This gene is regarded as a potential tumor suppressor gene. [provided by RefSeq].
Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
HDAC3, Histone deacetylase 3, RPD3-2, SMAP45
Immunogen :
HDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-412 amino acids from the C-terminal region of human HDAC3.
Specificity :
Human
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A affinity chromatography.
Immunogen: HDAC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 382-412 amino acids from the C-terminal region of human HDAC3.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
-20°C
Reference :
Minamiya, Y., et al. Tumour Biol. 31(5):533-539(2010)
Kim, H.C., et al. Cell. Mol. Life Sci. 67(20):3499-3510(2010)
Yang, Z., et al. Clin. Chem. Lab. Med. (2010) In press :
Kim, T., et al. Psychiatry Res 178(2):266-269(2010)
Adams, H., et al. Expert Opin. Ther. Targets 14(6):577-584(2010)
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/31/036478_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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