HBB, CT (HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7) (APC) | US Biological 036445-APC product information

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product summary

company name :

US Biological

product type :

antibody

product name :

HBB, CT (HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7) (APC)

catalog :

036445-APC

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

APC

reactivity :

human

product information

Catalog Number :

036445-APC

Product wo Prefix :

HBB, CT (HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7) (APC)

Host :

rabbit

Product Type :

Pab

Conjugate :

APC

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The alpha (HBA) and beta (HBB) loci determine the structure of the 2 types of polypeptide chains in adult hemoglobin, Hb A. The normal adult hemoglobin tetramer consists of two alpha chains and two beta chains. Mutant beta globin causes sickle cell anemia. Absence of beta chain causes beta-zero-thalassemia. Reduced amounts of detectable beta globin causes beta-plus-thalassemia. The order of the genes in the beta-globin cluster is 5'-epsilon -- gamma-G -- gamma-A -- delta -- beta--3'. Applications: Suitable for use in FLISA, Western Blot, Immunohistochemistry and Flow Cytometry. Other applications not tested. Recommended Dilutions: Immunohistochemistry: Formalin-fixed, paraffin-embedded sections Optimal dilutions to be determined by the researcher Storage and Stability: Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

HBB, Hemoglobin subunit beta, Beta-globin, Hemoglobin beta chain, LVV-hemorphin-7

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 80-107 in the C-terminal region of human HBB, UniProt Accession #P68871. Cellular Localization: Red blood cells.

Specificity :

Recognizes human HBB. Species Sequence Homology: bovine, chicken, equine, mouse, porcine, rat, rabbit, sheep

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 80-107 in the C-terminal region of human HBB, UniProt Accession #P68871. Cellular Localization: Red blood cells. Specificity: Recognizes human HBB. Species Sequence Homology: bovine, chicken, equine, mouse, porcine, rat, rabbit, sheep Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

FC FLISA IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). 2. Zhou, D., et al. Nat. Genet. 42(9):742-744(2010). 3. Onakoya, P.A., et al. Ear Nose Throat J 89(7):306-310(2010). 4. Belisario, A.R., et al. Acta Haematol. 124(3):162-170(2010). 5. Prakobkaew, N., et al. Acta Haematol. 124(2):115-119(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/23/036445-APC_1.jpg