HBA2, ID (HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain) (AP) | US Biological 036444-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

HBA2, ID (HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain) (AP)

catalog :

036444-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

036444-AP

Product wo Prefix :

HBA2, ID (HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

HBA2 located on chromosome 16 spans about 30 kb and includes seven loci: 5'- zeta - pseudozeta - mu - pseudoalpha-1 - alpha-2 - alpha-1 - theta - 3'. The alpha-2 (HBA2) and alpha-1 (HBA1) coding sequences are identical. These genes differ slightly over the 5' untranslated regions and the introns, but they differ significantly over the 3' untranslated regions. Two alpha chains plus two beta chains constitute HbA, which in normal adult life comprises about 97% of the total hemoglobin; alpha chains combine with delta chains to constitute HbA-2, which with HbF (fetal hemoglobin) makes up the remaining 3% of adult hemoglobin. Alpha thalassemias result from deletions of each of the alpha genes as well as deletions of both HBA2 and HBA1; some nondeletion alpha thalassemias have also been reported. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution: Immunohistochemistry: Formalin fixed paraffin embedded. Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Hu Mo

Alternate Name :

HBA1, Hemoglobin subunit alpha, Alpha-globin, Hemoglobin alpha chain

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 100-128 in the central region of human HBA2. Species Sequence Homology: monkey

Specificity :

Recognizes human HBA2. Species Crossreactivity: mouse

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 100-128 in the central region of human HBA2. Species Sequence Homology: monkey Specificity: Recognizes human HBA2. Species Crossreactivity: mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Sessa, R., et al. Am. J. Hematol. 85(2):143-144(2010) 2. Sharma, V., et al. Hematology 14(5):297-300(2009) 3. Waye, J.S., et al. Hemoglobin 33(6):519-522(2009) 4. Roy, P., et al. Hemoglobin 33(6):486-491(2009) 5. Joly, P., et al. Hemoglobin 33(3):196-205(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/47/036444-AP_1.jpg