This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
HAX1, CT (HAX1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1)
catalog :
036443
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
036443
Product wo Prefix :
HAX1, CT (HAX1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
The protein encoded by this gene is known to associate with hematopoietic cell-specific Lyn substrate 1, a substrate of Src family tyrosine kinases. It also interacts with the product of the polycystic kidney disease 2 gene, mutations in which are associated with autosomal-dominant polycystic kidney disease, and with the F-actin-binding protein, cortactin. It was earlier thought that this gene product is mainly localized in the mitochondria, however, recent studies indicate it to be localized in the cell body. Mutations in this gene result in autosomal recessive severe congenital neutropenia, also known as Kostmann disease. Two transcript variants encoding different isoforms have been found for this gene.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, ELISA
Recommended Dilution:
ELISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:10-50
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
HAX1, HS1BP1, HCLS1-associated protein X-1, HS1-associating protein X-1, HS1-binding protein 1
Immunogen :
HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the C-terminal region of human HAX1.
Specificity :
Human
Purity :
Purified by Protein A affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by Protein A affinity chromatography.
Immunogen: HAX1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 160-190 amino acids from the C-terminal region of human HAX1.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E IHC WB
Storage Temperature :
-20°C
Reference :
Johns, H.L., et al. J. Gen. Virol. 91 (PT 11), 2677-2686 (2010) :
Mekkawy, A.H., et al. Biochem. Biophys. Res. Commun. 399(4):738-743(2010)
Han, J., et al. J. Biol. Chem. 285(29):22461-22472(2010)
Germeshausen, M., et al. Haematologica 95(7):1207-1210(2010)
Burnicka-Turek, O., et al. BMC Cell Biol. 11, 28 (2010) :
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/36/036443_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
questions and comments