GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)

catalog :

036341

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

036341

Product wo Prefix :

GSTM5, NT (GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Cytosolic and membrane-bound forms of glutathione S-transferase are encoded by two distinct supergene families. At present, eight distinct classes of the soluble cytoplasmic mammalian glutathione S-transferases have been identified: alpha, kappa, mu, omega, pi, sigma, theta and zeta. This gene encodes a glutathione S-transferase that belongs to the mu class. The mu class of enzymes functions in the detoxification of electrophilic compounds, including carcinogens, therapeutic drugs, environmental toxins and products of oxidative stress, by conjugation with glutathione. The genes encoding the mu class of enzymes are organized in a gene cluster on chromosome 1p13.3 and are known to be highly polymorphic. These genetic variations can change an individual's susceptibility to carcinogens and toxins as well as affect the toxicity and efficacy of certain drugs. Diversification of these genes has occurred in regions encoding substrate-binding domains, as well as in tissue expression patterns, to accommodate an increasing number of foreign compounds. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry: 1:10-1:50 Flow Cytometry: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

GSTM5, Glutathione S-transferase Mu 5, GST class-mu 5, GSTM5-5

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 14-43 from the N-terminal region of human GSTM5.

Specificity :

Recognizes human GSTM5.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 14-43 from the N-terminal region of human GSTM5. Specificity: Recognizes human GSTM5. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IHC WB

Storage Temperature :

-20°C

Reference :

1. Wang, Y., et al. J. Hum. Genet. 55(8):490-494(2010) 2. Yu, K.D., et al. Breast Cancer Res. Treat. 121(2):485-496(2010) 3. Davila, S., et al. Genes Immun. 11(3):232-238(2010) 4. Moyer, A.M., et al. Cancer Epidemiol. Biomarkers Prev. 19(3):811-821(2010) 5. Saito, A., et al. J. Hum. Genet. 54(6):317-323(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/20/036341_1.png