Glypican 3 (GPC3), CT (GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

Glypican 3 (GPC3), CT (GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3)

catalog :

036110

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

036110

Product wo Prefix :

Glypican 3 (GPC3), CT (GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

GPC3 is a cell surface proteoglycan that bears heparan sulfate. This protein may be involved in the suppression/modulation of growth in the predominantly mesodermal tissues and organs, and may play a role in the modulation of IGF2 interactions with its receptor and thereby modulate its function. Members of the glypican-related integral membrane proteoglycan family contain a core protein anchored to the cytoplasmic membrane via a glycosyl phosphatidylinositol (GPI) linkage. These proteins may play a role in the control of cell division, growth regulation, and tumor predisposition. Deletion mutations in GPC3 are the cause of Simpson-Golabi-Behmel syndrome (SGBS), also known as Simpson dysmorphia syndrome (SDYS). SGBS is a condition characterized by pre- and postnatal overgrowth (gigantism) with visceral and skeletal anomalies. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-100 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Hu Mo

Alternate Name :

GPC3, OCI5, Glypican-3, GTR2-2, Intestinal protein OCI-5, MXR7, Secreted glypican-3

Immunogen :

GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between amino acids 530-560of human GPC3.

Specificity :

Human, mouse

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein G affinity chromatography. Immunogen: GPC3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected between amino acids 530-560of human GPC3. Specificity: Human, mouse Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Nakatsura, T., et al., Clin. Cancer Res. 10(19):6612-6621 (2004). Boily, G., et al., Br. J. Cancer 90(8):1606-1611 (2004). Wichert, A., et al., Oncogene 23(4):945-955 (2004). Midorikawa, Y., et al., Int. J. Cancer 103(4):455-465 (2003). Sung, Y.K., et al., Cancer Sci. 94(3):259-262 (2003).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/41/036110_1.jpg