GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2)

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product summary

company name :

US Biological

product type :

antibody

product name :

GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2)

catalog :

036008

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

036008

Product wo Prefix :

GFRA2, CT (GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Glial cell line-derived neurotrophic factor (GDNF) and neurturin (NTN) are two structurally related, potent neurotrophic factors that play key roles in the control of neuron survival and differentiation. The protein encoded by this gene is a member of the GDNF receptor family. It is a glycosylphosphatidylinositol(GPI)-linked cell surface receptor for both GDNF and NTN, and mediates activation of the RET tyrosine kinase receptor. This encoded protein acts preferentially as a receptor for NTN compared to its other family member, GDNF family receptor alpha 1. This gene is a candidate gene for RET-associated diseases. Multiple transcript variants encoding different isoforms have been found for this gene. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

GFRA2, GDNFRB, RETL2, TRNR2, GDNF family receptor alpha-2, GDNF receptor beta, Neurturin receptor alpha, RET ligand 2, TGF-beta-related neurotrophic factor receptor 2

Immunogen :

GFRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-390 amino acids from the C-terminal region of human GFRA2.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: GFRA2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 360-390 amino acids from the C-terminal region of human GFRA2. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Souza, R.P., et al. J Psychiatr Res 44(11):700-706(2010) Souza, R.P., et al. Psychopharmacology (Berl.) 210(3):347-354(2010) Buysschaert, I.D., et al. Allergy 65(5):616-622(2010) Lavedan, C., et al. Mol. Psychiatry 14(8):804-819(2009) Volpi, S., et al. J Clin Psychiatry 70(6):801-809(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/30/036008_1.jpg