GABARAPL2, CT (GATE16, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein) (AP) | US Biological 035844-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

GABARAPL2, CT (GATE16, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein) (AP)

catalog :

035844-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

035844-AP

Product wo Prefix :

GABARAPL2, CT (GATE16, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Membrane proteins located on vesicles (v-SNAREs) and on the target membrane (t-SNAREs) mediate specific recognition and, possibly, fusion between a transport vesicle and its target membrane. The activity of SNARE molecules is regulated by several soluble cytosolic proteins. We have cloned a bovine brain cDNA encoding a conserved 117 amino acid polypeptide, denoted Golgi-associated ATPase Enhancer of 16 kDa (GATE-16), that functions as a soluble transport factor. GATE-16 interacts with N-ethylmaleimidesensitive factor (NSF) and significantly stimulates its ATPase activity. It also interacts with the Golgi v-SNARE GOS-28 in an NSF-dependent manner. We propose that GATE-16 modulates intra-Golgi transport through coupling between NSF activity and SNAREs activation. Applications: Suitable for use in Immunohistochemistry, ELISA Recommended Dilution: ELISA1:1,000 Immunohistochemistry: 1:10-50 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

GATE16, GABA(A) receptor-associated protein-like 2, Ganglioside expression factor 2, GEF-2, General protein transport factor p16, MAP1 light chain 3-related protein

Immunogen :

GATE16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GABARAPL2.

Specificity :

Human

Purity :

Purified by peptide immunoaffinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by peptide immunoaffinity chromatography. Immunogen: GATE16 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide selected from the C-terminal region of human GABARAPL2. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC

Storage Temperature :

4°C Do Not Freeze

Reference :

Sou,Y.S., J. Biol. Chem. 281 (6), 3017-3024 (2006) Mehrle,A., Nucleic Acids Res. 34 (DATABASE ISSUE), D415-D418 (2006) Wiemann,S., Genome Res. 14 (10B), 2136-2144 (2004) Sagiv,Y., EMBO J. 19 (7), 1494-1504 (2000)