FGFRL1, NT (FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

FGFRL1, NT (FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5)

catalog :

035644

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

035644

Product wo Prefix :

FGFRL1, NT (FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a member of the fibroblast growth factor receptor (FGFR) family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein would consist of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. A marked difference between this gene product and the other family members is its lack of a cytoplasmic tyrosine kinase domain. The result is a transmembrane receptor that could interact with other family members and potentially inhibit signaling. Multiple alternatively spliced transcript variants encoding the same isoform have been found for this gene. Applications: Suitable for use in Western Blot, Immunohistochemistry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

FGFRL1, FGFR5, FHFR, Fibroblast growth factor receptor-like 1, FGF homologous factor receptor, FGFR-like protein, Fibroblast growth factor receptor 5

Immunogen :

FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from the N-terminal region of human FGFRL1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: FGFRL1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 138-168 amino acids from the N-terminal region of human FGFRL1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

Bailey, S.D., et al. Diabetes Care (2010) In press : Liu, C.Y., et al. Carcinogenesis 31(7):1259-1263(2010) LopezJimenez, N., et al. Hum. Genet. 127(3):325-336(2010) Steinberg, F., et al. J. Biol. Chem. 285(3):2193-2202(2010) Talmud, P.J., et al. Am. J. Hum. Genet. 85(5):628-642(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/47/035644_1.jpg