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product summary
company name :
US Biological
product type :
antibody
product name :
FGFR1, CT (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Basic fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, N-sam, Proto-oncogene c-Fgr, CD331)
catalog :
035635
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
nonconjugated
reactivity :
human
product information
Catalog Number :
035635
Product wo Prefix :
FGFR1, CT (FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Basic fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, N-sam, Proto-oncogene c-Fgr, CD331)
Host :
rabbit
Product Type :
Pab
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
FGFR1 is a member of the fibroblast growth factor receptor family, where amino acid sequence is highly conserved between members and throughout evolution. FGFR family members differ from one another in their ligand affinities and tissue distribution. A full-length representative protein consists of an extracellular region, composed of three immunoglobulin-like domains, a single hydrophobic membrane-spanning segment and a cytoplasmic tyrosine kinase domain. The extracellular portion of the protein interacts with fibroblast growth factors, setting in motion a cascade of downstream signals, ultimately influencing mitogenesis and differentiation. This particular family member binds both acidic and basic fibroblast growth factors and is involved in limb induction.
Applications:
Suitable for use in Western Blot, Flow Cytometry, Immunohistochemistry and ELISA. Other applications not tested.
Recommended Dilutions:
Western Blot: 1:1000
Flow Cytometry: 1:10-1:50
Immunohistochemistry (FFPE): 1:10-1:50
Optimal dilutions to be determined by the researcher.
Storage and Stability:
May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.
Calc Crossreactivity :
Hu
Alternate Name :
FGFR1, BFGFR, CEK, FGFBR, FLG, FLT2, HBGFR, Fibroblast growth factor receptor 1, Basic fibroblast growth factor receptor 1, Fms-like tyrosine kinase 2, N-sam, Proto-oncogene c-Fgr, CD331
Immunogen :
His fusion protein corresponding to human FGFR1
Specificity :
Recognizes human FGFR1.
Purity :
Purified by ammonium sulfate precipitation.
Form :
Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.
Purity: Purified by ammonium sulfate precipitation.
Immunogen: His fusion protein corresponding to human FGFR1
Specificity: Recognizes human FGFR1.
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
E FC IHC WB
Storage Temperature :
-20°C
Reference :
1. Jiao, J., et al., Arch. Biochem. Biophys. 410(2):187-200 (2003). 2. Fu, L., et al., J. Comp. Neurol. 462(2):265-273 (2003). 3. Lundin, L., et al., Exp. Cell Res. 287(1):190-198 (2003). 4. Kiselyov, V.V., et al., Structure (Camb.) 11(6):691-701 (2003). 5. Baumann, H., et al., J. Biol. Chem. 278(18):16198-16208 (2003).
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/48/035635_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
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