FAP (FAP, Seprase, 170kD melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

FAP (FAP, Seprase, 170kD melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease)

catalog :

035512

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

035512

Product wo Prefix :

FAP (FAP, Seprase, 170kD melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is a homodimeric integral membrane gelatinase belonging to the serine protease family. It is selectively expressed in reactive stromal fibroblasts of epithelial cancers, granulation tissue of healing wounds, and malignant cells of bone and soft tissue sarcomas. This protein is thought to be involved in the control of fibroblast growth or epithelial-mesenchymal interactions during development, tissue repair, and epithelial carcinogenesis. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

FAP, Seprase, 170kD melanoma membrane-bound gelatinase, Fibroblast activation protein alpha, Integral membrane serine protease

Immunogen :

Human FAP (Accession #NP004451).

Specificity :

Recognizes human FAP.

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: Human FAP (Accession #NP004451). Specificity: Recognizes human FAP. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Rose, J.E., et al. Mol. Med. 16 (7-8), 247-253 (2010) : Ospelt, C., et al. Arthritis Rheum. 62(5):1224-1235(2010) Stremenova, J., et al. Int. J. Oncol. 36(2):351-358(2010) Chen, H., et al. Exp. Mol. Pathol. 87(3):189-194(2009) Dohi, O., et al. Histopathology 55(4):432-440(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/035512_1.jpg