F9, ID (F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain)

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product summary

company name :

US Biological

product type :

antibody

product name :

F9, ID (F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain)

catalog :

035312

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

035312

Product wo Prefix :

F9, ID (F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-295 in the central region of human F9.

Specificity :

Recognizes human F9.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-295 in the central region of human F9. Specificity: Recognizes human F9. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10): 2250-2253 (2010). 2. Yang, L., et al., J. Biol. Chem. 285(37): 28,488-28,495 (2010). 3. Kao, C.Y., et al., Thromb. Haemost. 104(2): 355-365 (2010). 4. Roberts, K.E., et al., Gastroenterology 139(1): 130-139 (2010). 5. Arellano, A.R., et al., J. Thromb. Haemost. 8(5): 1132-1134 (2010).

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/8/035312_1.jpg