antibody

F9, ID (F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain) (AP)

035312-AP

200 ul

polyclonal

domestic rabbit

AP

F9, ID (F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain) (AP)

rabbit

Pab

AP

Antibodies

200 ul

IgG

This gene encodes vitamin K-dependent coagulation factor IX that circulates in the blood as an inactive zymogen. This factor is converted to an active form by factor XIa, which excises the activation peptide and thus generates a heavy chain and a light chain held together by one or more disulfide bonds. The role of this activated factor IX in the blood coagulation cascade is to activate factor X to its active form through interactions with Ca+2 ions, membrane phospholipids, and factor VIII. Alterations of this gene, including point mutations, insertions and deletions, cause factor IX deficiency, which is a recessive X-linked disorder, also called hemophilia B or Christmas disease. Applications: Suitable for use in Western Blot and ELISA. Other applications have not been tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

F9, Coagulation factor IX, Christmas factor, Plasma thromboplastin component, Coagulation factor IXa light chain, Coagulation factor IXa heavy chain

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-295 in the central region of human F9.

Recognizes human F9.

Purified by Protein A and peptide affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 266-295 in the central region of human F9. Specificity: Recognizes human F9. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E WB

4°C Do Not Freeze

1. Bailey, S.D., et al. Diabetes Care 33(10): 2250-2253 (2010). 2. Yang, L., et al., J. Biol. Chem. 285(37): 28,488-28,495 (2010). 3. Kao, C.Y., et al., Thromb. Haemost. 104(2): 355-365 (2010). 4. Roberts, K.E., et al., Gastroenterology 139(1): 130-139 (2010). 5. Arellano, A.R., et al., J. Thromb. Haemost. 8(5): 1132-1134 (2010).

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