ETS1, NT (ETS1, EWSR2, Protein C-ets-1, p54) | US Biological 035249 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ETS1, NT (ETS1, EWSR2, Protein C-ets-1, p54)

catalog :

035249

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

035249

Product wo Prefix :

ETS1, NT (ETS1, EWSR2, Protein C-ets-1, p54)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

ETS transcriptions factors, such as ETS1, regulate numerous genes and are involved in stem cell development, cell senescence and death, and tumorigenesis. The conserved ETS domain within these proteins is a winged helix-turn-helix DNA-binding domain that recognizes the core consensus DNA sequence GGAA/T of target genes (summary by Dwyer et al., 2007 [PubMed 17986575]). Applications: Suitable for use in Western Blot, Immunofluorescence, Flow Cytometry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Flow Cytometry: 1:10-1:50 Immunofluorescence: 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

ETS1, EWSR2, Protein C-ets-1, p54

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 43-70 in the N-terminal region of human ETS1, UniProt Accession #P14921. Species sequence homology: mouse, rat

Specificity :

Recognizes human ETS1.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 43-70 in the N-terminal region of human ETS1, UniProt Accession #P14921. Species sequence homology: mouse, rat Specificity: Recognizes human ETS1. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IF WB

Storage Temperature :

-20°C

Reference :

1. Harris, T.A., et al. Arterioscler. Thromb. Vasc. Biol. 30(10):1990-1997(2010) 2. He, C.F., et al. Lupus 19(10):1181-1186(2010) 3. Russell, L., et al. Cytokine 51(3):217-226(2010) 4. Li, T., et al. Pharm Biol 48(2):161-165(2010) 5. Kunderfranco, P., et al. PLoS ONE 5 (5), E10547 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/11/035249_1.png

Picture4 Text :

Confocal immunofluorescent analysis with MCF-7 cells using 035249 followed by Alexa Fluor® 488-conjugated goat anti-rabbit lgG (green). DAPI was used to stain the cell nuclear (blue).