ErbB2, NT (ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340) (AP) | US Biological 035161-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

ErbB2, NT (ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340) (AP)

catalog :

035161-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

035161-AP

Product wo Prefix :

URL USB :

www.usbio.net/antibodies/035161-AP/ErbB2-NT-ERBB2-HER2-MLN19-NEU-NGL-Receptor-tyrosineprotein-kinase-erbB2-Metastatic-lymph-node-gene-19-protein-Protooncogene-Neu-Protooncogene-cErbB2-Tyrosine-kinasetype-cell-surface-receptor-HER2-p185erbB2-CD340-AP

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

ErbB2, a member of the EGF receptor family, is an essential component of a neuregulin-receptor complex, although neuregulins do not interact with it alone. GP30 is a potential ligand for this receptor. This protein is not activated by EGF, TGF-alpha and amphiregulin. ErbB2 potentially forms a heterodimer with each of the other ERBB receptors. An Interaction with PRKCABP has been suggested. Ligand-binding to this Type I membrane protein may increase phosphorylation on tyrosine residues. Applications:. Suitable for use in Western Blot, Immunohistochemistry, ELISA. Recommended Dilution:. ELISA: 1:1,000. Western Blot: 1:100-500. Immunohistochemistry: 1:50-100. 1:10-50. Storage and Stability:. Store product at 4 C. DO NOT FREEZE! Stable at 4 C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

ERBB2, HER2, MLN19, NEU, NGL, Receptor tyrosine-protein kinase erbB-2, Metastatic lymph node gene 19 protein, Proto-oncogene Neu, Proto-oncogene c-ErbB-2, Tyrosine kinase-type cell surface receptor HER2, p185erbB2, CD340

Immunogen :

ErbB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30~59 amino acids from the N-terminal region of human HER2/ErbB2.

Specificity :

Human

Purity :

Purified by Protein G affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab. Isotype: IgG. Host: rabbit. Source: human. Concentration: As reported. Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein G affinity chromatography. Immunogen: ErbB2 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 30~59 amino acids from the N-terminal region of human HER2/ErbB2. Specificity: Human. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

4 C Do Not Freeze

Reference :

Ehsani, A., et al., Genomics 15(2):426-429 (1993). Yamamoto, T., et al., Nature 319(6050):230-234 (1986). Coussens, L., et al., Science 230(4730):1132-1139 (1985). Semba, K., et al., Proc. Natl. Acad. Sci. U.S.A. 82(19):6497-6501 (1985).

Picture 1 File Name :

usbio-images.r.worldssl.net/prodimages/24/035161-AP_1.jpg

Picture4 Text :

Formalin-fixed and paraffin-embedded human breast carcinoma tissue reacted with HER2/ErbB2 antibody (N-term) , which was peroxidase-conjugated to the secondary antibody, followed by DAB staining. This data demonstrates the use of this antibody for immunohistochemistry; clinical relevance has not been evaluated.