EPOR, ID (EPOR, Erythropoietin receptor) (AP) | US Biological 035132-AP product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

EPOR, ID (EPOR, Erythropoietin receptor) (AP)

catalog :

035132-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

035132-AP

Product wo Prefix :

EPOR, ID (EPOR, Erythropoietin receptor) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes the erythropoietin receptor which is a member of the cytokine receptor family. Upon erythropoietin binding, this receptor activates Jak2 tyrosine kinase which activates different intracellular pathways including: Ras/MAP kinase, phosphatidylinositol 3-kinase and STAT transcription factors. The stimulated erythropoietin receptor appears to have a role in erythroid cell survival. Defects in the erythropoietin receptor may produce erythroleukemia and familial erythrocytosis. Dysregulation of this gene may affect the growth of certain tumors. Alternate splicing results in multiple transcript variants. Applications: Suitable for use in Western Blot and ELISA. Other applications not tested. Recommended Dilution: Optimal dilutions to be determined by the researcher. Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

EPOR, Erythropoietin receptor

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 329-357 in the central region of human EPOR, Swiss/UniProt Accession: P19235.

Specificity :

Recognizes human EPOR.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 329-357 in the central region of human EPOR, Swiss/UniProt Accession: P19235. Specificity: Recognizes human EPOR. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

1. Lim, A.C., et al. Biochemistry 49(18):3797-3804 (2010). 2. Perrotta, S., et al. PLoS ONE 5 (8), E12015 (2010). 3. Khankin, E.V., et al. PLoS ONE 5 (2), E9246 (2010). 4. Wincewicz, A., et al. Folia Histochem. Cytobiol. 47(3):425-430 (2009). 5. Ketteler, R., et al. J. Biol. Chem. 278(4):2654-2660 (2003)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/15/035132-AP_1.jpg