EIF4EBP1, ID (EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1)

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product summary

company name :

US Biological

product type :

antibody

product name :

EIF4EBP1, ID (EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1)

catalog :

035015

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

035015

Product wo Prefix :

EIF4EBP1, ID (EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes one member of a family of translation repressor proteins. The protein directly interacts with eukaryotic translation initiation factor 4E (eIF4E), which is a limiting component of the multisubunit complex that recruits 40S ribosomal subunits to the 5' end of mRNAs. Interaction of this protein with eIF4E inhibits complex assembly and represses translation. This protein is phosphorylated in response to various signals including UV irradiation and insulin signaling, resulting in its dissociation from eIF4E and activation of mRNA translation. [provided by RefSeq]. Applications: Suitable for use in Western Blot, Immunohistochemistry, Flow Cytometry, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:50-100 Immunohistochemistry: 1:10-50 Flow Cytometry: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

EIF4EBP1, Eukaryotic translation initiation factor 4E-binding protein 1, Phosphorylated heat- and acid-stable protein regulated by insulin 1

Immunogen :

EIF4EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-69 amino acids from the Central region of human EIF4EBP1.

Specificity :

Human

Purity :

Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by saturated ammonium sulfate precipitation followed by dialysis against PBS. Immunogen: EIF4EBP1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-69 amino acids from the Central region of human EIF4EBP1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E FC IHC WB

Storage Temperature :

-20°C

Reference :

She, Q.B., et al. Cancer Cell 18(1):39-51(2010) Aoyagi, M., et al. Proc. Natl. Acad. Sci. U.S.A. 107(6):2640-2645(2010) Naukkarinen, J., et al. PLoS Genet. 6 (6), E1000976 (2010) : Kumar, A., et al. PLoS ONE 5 (1), E8730 (2010) : Villalonga, P., et al. J. Biol. Chem. 284(51):35287-35296(2009)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/14/035015_1.jpg