DSG2, CT (DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC)

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

DSG2, CT (DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC)

catalog :

034828

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

034828

Product wo Prefix :

DSG2, CT (DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Desmosomes are cell-cell junctions between epithelial, myocardial, and certain other cell types. This gene product is a calcium-binding transmembrane glycoprotein component of desmosomes in vertebrate epithelial cells. Currently, three desmoglein subfamily members have been identified and all are members of the cadherin cell adhesion molecule superfamily. These desmoglein gene family members are located in a cluster on chromosome 18. This second family member is expressed in colon, colon carcinoma, and other simple and stratified epithelial-derived cell lines. Mutations in this gene have been associated with arrhythmogenic right ventricular dysplasia, familial, 10. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilutions: Western Blot: 1:1000 Immunohistochemistry (FFPE): 1:10-1:50 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

DSG2, CDHF5, Desmoglein-2, Cadherin family member 5, HDGC

Immunogen :

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 829-857 in the C-terminal region of human DSG2, UniProt Accession #Q14126.

Specificity :

Recognizes human DSG2.

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As Reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As Reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 829-857 in the C-terminal region of human DSG2, UniProt Accession #Q14126. Specificity: Recognizes human DSG2. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Bailey, S.D., et al. Diabetes Care 33(10):2250-2253(2010). 2. Fressart, V., et al. Europace 12(6):861-868(2010). 3. Schlegel, N., et al. Am. J. Physiol. Gastrointest. Liver Physiol. 298 (5), G774-G783 (2010). 4. Cox, M.G., et al. Circ Arrhythm Electrophysiol 3(2):126-133(2010). 5. Buxens, A., et al. Scand J Med Sci Sports (2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/16/034828_1.jpg