DNMT3A, CT (V897) (DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA)

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product summary

company name :

US Biological

product type :

antibody

product name :

DNMT3A, CT (V897) (DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA)

catalog :

034748

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

034748

Product wo Prefix :

DNMT3A, CT (V897) (DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. This gene encodes a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated. Alternative splicing results in multiple transcript variants encoding different isoforms. [provided by RefSeq]. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA

Immunogen :

DNMT3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 871-900 amino acids from the C-terminal region of human DNMT3A.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: DNMT3A antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 871-900 amino acids from the C-terminal region of human DNMT3A. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

-20°C

Reference :

Holz-Schietinger, C., et al. J. Biol. Chem. 285(38):29091-29100(2010) Kelemen, L.E., et al. Cancer Epidemiol. Biomarkers Prev. 19(7):1822-1830(2010) Park, C.W., et al. J Cardiovasc Transl Res 3(3):290-295(2010) Haggarty, P., et al. PLoS ONE 5 (6), E11329 (2010) : Zhao, Z., et al. J. Biomed. Biotechnol. 2010, 737535 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/22/034748_1.jpg