This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.
product summary
company name :
US Biological
product type :
antibody
product name :
Dnmt3a (DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA) (APC)
catalog :
034745-APC
quantity :
200 ul
clonality :
polyclonal
host :
domestic rabbit
conjugate :
APC
reactivity :
human
product information
Catalog Number :
034745-APC
Product wo Prefix :
Dnmt3a (DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA) (APC)
Host :
rabbit
Product Type :
Pab
Conjugate :
APC
Category :
Antibodies
Size1 :
200 ul
Isotype :
IgG
Desc1 :
CpG methylation is an epigenetic modification that is important for embryonic development, imprinting, and X-chromosome inactivation. Studies in mice have demonstrated that DNA methylation is required for mammalian development. Dnmt3a is a DNA methyltransferase that is thought to function in de novo methylation, rather than maintenance methylation. The protein localizes to the cytoplasm and nucleus and its expression is developmentally regulated.
Applications:
Suitable for use in Western Blot, Immunohistochemistry, FLISA
Recommended Dilution:
FLISA: 1:1,000
Western Blot: 1:100-500
Immunohistochemistry: 1:50-100
Storage and Stability:
Store product at 4°C in the dark. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. Caution: APC conjugates are sensitive to light. For maximum recovery of product, centrifuge the original vial prior to removing the cap.
Note: Applications are based on unconjugated antibody.
Calc Crossreactivity :
Hu
Alternate Name :
DNMT3A, DNA (cytosine-5)-methyltransferase 3A, DNA methyltransferase HsaIIIA
Immunogen :
Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465~494 amino acids from the central region of human Dnmt3a.
Specificity :
Human
Purity :
Purified by Protein G affinity chromatography.
Form :
Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Concentration :
As reported
Desc2 :
Product Type: Pab
Isotype: IgG
Host: rabbit
Source: human
Concentration: As reported
Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Allophycocyanin (APC).
Purity: Purified by Protein G affinity chromatography.
Immunogen: Dnmt3a antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 465~494 amino acids from the central region of human Dnmt3a.
Specificity: Human
Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.
Calc Applications Abbrev :
FL IHC WB
Storage Temperature :
4°C Do Not Freeze
Reference :
Xie, S., et al., Gene 236(1):87-95 (1999). Robertson, K.D., et al., Nucleic Acids Res. 27(11):2291-2298 (1999).
Picture 1 File Name :
https://usbio-images.r.worldssl.net/prodimages/29/034745-APC_1.jpg
company information
US Biological
4 Technology Way
Salem, MA01970
Salem, MA01970
service@usbio.net
https://www.usbio.net800-520-3011
headquarters: USA
United States Biological is a primary brand for the Life Science Industry. We are committed to reducing the cost of research with value, integrity and a truly personal buying experience.
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