DLK (DLK1, DLK, Protein delta homolog 1, pG2, Fetal antigen 1) | US Biological 034665 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

DLK (DLK1, DLK, Protein delta homolog 1, pG2, Fetal antigen 1)

catalog :

034665

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

034665

Product wo Prefix :

DLK (DLK1, DLK, Protein delta homolog 1, pG2, Fetal antigen 1)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

This gene encodes a transmembrane protein containing six epidermal growth factor repeats. The protein is involved in the differentiation of several cell types, including adipocytes; it is also thought to be a tumor suppressor. It is one of several imprinted genes located in a region of on chr 14q32. Certain mutations in this imprinted region can cause phenotypes similar to maternal and paternal uniparental disomy of chromosome 14 (UPD14). This gene is expressed from the paternal allele. A polymorphism within this gene has been associated with child and adolescent obesity. The mode of inheritance for this polymorphism is polar overdominance; this non-Mendelian inheritance pattern was first described in sheep with the callipyge phenotype, which is characterized by muscle hypertrophy and decreased fat mass. Applications: Suitable for use in Western Blot, Immunohistochemistry and ELISA. Other applications have not been tested. Recommended Dilution: Western Blot: 1:1000 Immunohistochemistry: 1:50-1:100 Optimal dilutions to be determined by the researcher. Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months after receipt. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

DLK1, DLK, Protein delta homolog 1, pG2, Fetal antigen 1

Immunogen :

Recombinant protein corresponding to human DLK. Uniprot: P80370

Specificity :

Recognizes human DLK.

Purity :

Purified by Protein A and peptide affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A and peptide affinity chromatography. Immunogen: Recombinant protein corresponding to human DLK. Uniprot: P80370 Specificity: Recognizes human DLK. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IHC WB

Storage Temperature :

-20°C

Reference :

1. Yanai, H., et al. J. Biochem. 148(1):854-92(2010) 2. Yu, F., et al. Liver Int. 30(5):703-714(2010) 3. Akiyama, J., et al. Biochem. Biophys. Res. Commun. 393(4):662-667(2010) 4. Wermter, A.K., et al. Eur. J. Hum. Genet. 16(9):1126-1134(2008) 5. Charlier, C., et al. Genome Res. 11(5):850-862(2001)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/10/034665_1.png