DEFA3, CT (DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP 3-56, Neutrophil defensin 2, HNP-2) (AP) | US Biological 034571-AP product information

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product summary

company name :

US Biological

product type :

antibody

product name :

DEFA3, CT (DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP 3-56, Neutrophil defensin 2, HNP-2) (AP)

catalog :

034571-AP

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

reactivity :

human

product information

Catalog Number :

034571-AP

Product wo Prefix :

DEFA3, CT (DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP 3-56, Neutrophil defensin 2, HNP-2) (AP)

Host :

rabbit

Product Type :

Pab

Conjugate :

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

Defensins are a family of microbicidal and cytotoxic peptides thought to be involved in host defense. They are abundant in the granules of neutrophils and also found in the epithelia of mucosal surfaces such as those of the intestine, respiratory tract, urinary tract, and vagina. Members of the defensin family are highly similar in protein sequence and distinguished by a conserved cysteine motif. The protein encoded by this gene, defensin, alpha 3, is found in the microbicidal granules of neutrophils and likely plays a role in phagocyte-mediated host defense. Several alpha defensin genes are clustered on chromosome 8. This gene differs from defensin, alpha 1 by only one amino acid. This gene and the gene encoding defensin, alpha 1 are both subject to copy number variation. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Calc Crossreactivity :

Alternate Name :

DEFA3, DEF3, Neutrophil defensin 3, Defensin, alpha 3, HNP-3, HP 3-56, Neutrophil defensin 2, HNP-2

Immunogen :

DEFA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the C-terminal region of human DEFA3.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: DEFA3 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 38-66 amino acids from the C-terminal region of human DEFA3. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E WB

Storage Temperature :

4°C Do Not Freeze

Reference :

Han, S., et al. Hum. Immunol. 71(7):727-730(2010) Chen, Q., et al. Anesthesiology 112(6):1428-1434(2010) Rajaraman, P., et al. Cancer Epidemiol. Biomarkers Prev. 19(5):1356-1361(2010) Paslakis, G., et al. Nephron Exp. Nephrol. 115 (4), E96-E100 (2010) : Rodriguez-Garcia, M., et al. PLoS ONE 5 (2), E9436 (2010) :

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/42/034571-AP_1.jpg