antibody

CXCL11, CT (CXCL11, ITAC, SCYB11, SCYB9B, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11) (AP)

034380-AP

200 ul

polyclonal

domestic rabbit

AP

CXCL11, CT (CXCL11, ITAC, SCYB11, SCYB9B, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11) (AP)

rabbit

Pab

AP

Antibodies

200 ul

IgG

Chemokines are a group of small (approximately 8 to 14 kD), mostly basic, structurally related molecules that regulate cell trafficking of various types of leukocytes through interactions with a subset of 7-transmembrane, G protein-coupled receptors. Chemokines also play fundamental roles in the development, homeostasis, and function of the immune system, and they have effects on cells of the central nervous system as well as on endothelial cells involved in angiogenesis or angiostasis. Chemokines are divided into 2 major subfamilies, CXC and CC. This gene is a CXC member of the chemokine superfamily. Its encoded protein induces a chemotactic response in activated T-cells and is the dominant ligand for CXC receptor-3. The gene encoding this protein contains 4 exons and at least three polyadenylation signals which might reflect cell-specific regulation of expression. IFN-gamma is a potent inducer of transcription of this gene. Applications: Suitable for use in Western Blot, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Storage and Stability: Store product at 4°C. DO NOT FREEZE! Stable at 4°C for 12 months after receipt as an undiluted liquid. Dilute required amount only prior to immediate use. Further dilutions can be made in assay buffer. For maximum recovery of product, centrifuge the original vial prior to removing the cap. Note: Applications are based on unconjugated antibody.

Hu

CXCL11, ITAC, SCYB11, SCYB9B, C-X-C motif chemokine 11, Beta-R1, H174, Interferon gamma-inducible protein 9, Interferon-inducible T-cell alpha chemoattractant, Small-inducible cytokine B11

KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 64-93 in the C-terminal region of human CXCL11, UniProt Accession #O14625.

Recognizes human CXCL11.

Purified by Protein A affinity chromatography.

Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP).

As reported

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2. No preservative added. Labeled with Alkaline Phophatase (AP). Purity: Purified by Protein A affinity chromatography. Immunogen: KLH-conjugated synthetic peptide mapping to a fragment of residues within amino acids 64-93 in the C-terminal region of human CXCL11, UniProt Accession #O14625. Specificity: Recognizes human CXCL11. Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

E WB

4°C Do Not Freeze

1. Rot, A. Front. Biosci. 15, 645-660 (2010). 2. Luttrell, L.M. Mol. Biotechnol. 39(3):239-264 (2008). 3. Kouroumalis, A., et al. J. Immunol. 175(8):5403-5411 (2005). 4. Booth, V., et al. Protein Sci. 13(8):2022-2028 (2004). 5. Colvin, R.A., et al. J. Biol. Chem. 279(29):30219-30227 (2004)

https://usbio-images.r.worldssl.net/prodimages/33/034380-AP_1.jpg