CTNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin) | US Biological 034332 product information

This webpage contains legacy information. The product is either no longer available from the supplier or has been delisted at Labome.

product summary

company name :

US Biological

product type :

antibody

product name :

CTNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

catalog :

034332

quantity :

200 ul

clonality :

polyclonal

host :

domestic rabbit

conjugate :

nonconjugated

reactivity :

human

product information

Catalog Number :

034332

Product wo Prefix :

CTNB1, CT (CTNNB1, CTNNB, Catenin beta-1, Beta-catenin)

Host :

rabbit

Product Type :

Pab

Category :

Antibodies

Size1 :

200 ul

Isotype :

IgG

Desc1 :

The protein encoded by this gene is part of a complex of proteins that constitute adherens junctions (AJs). AJs are necessary for the creation and maintenance of epithelial cell layers by regulating cell growth and adhesion between cells. The encoded protein also anchors the actin cytoskeleton and may be responsible for transmitting the contact inhibition signal that causes cells to stop dividing once the epithelial sheet is complete. Finally, this protein binds to the product of the APC gene, which is mutated in adenomatous polyposis of the colon. Mutations in this gene are a cause of colorectal cancer (CRC), pilomatrixoma (PTR), medulloblastoma (MDB), and ovarian cancer. Three transcript variants encoding the same protein have been found for this gene. Applications: Suitable for use in Western Blot, Immunohistochemistry, Immunofluorescence, ELISA Recommended Dilution: ELISA: 1:1,000 Western Blot: 1:100-500 Immunohistochemistry: 1:10-50 Immunofluorescence: 1:10-50 Storage and Stability: May be stored at 4°C for short-term only. Aliquot to avoid repeated freezing and thawing. Store at -20°C. Aliquots are stable for 12 months. For maximum recovery of product, centrifuge the original vial after thawing and prior to removing the cap.

Calc Crossreactivity :

Alternate Name :

CTNNB1, CTNNB, Catenin beta-1, Beta-catenin

Immunogen :

CTNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 653-681 amino acids from the C-terminal region of human CTNB1.

Specificity :

Human

Purity :

Purified by Protein A affinity chromatography.

Form :

Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide.

Concentration :

As reported

Desc2 :

Product Type: Pab Isotype: IgG Host: rabbit Source: human Concentration: As reported Form: Supplied as a liquid in PBS, pH 7.2, 0.09% sodium azide. Purity: Purified by Protein A affinity chromatography. Immunogen: CTNB1 antibody is generated from rabbits immunized with a KLH conjugated synthetic peptide between 653-681 amino acids from the C-terminal region of human CTNB1. Specificity: Human Important Note: This product as supplied is intended for research use only, not for use in human, therapeutic or diagnostic applications without the expressed written authorization of United States Biological.

Calc Applications Abbrev :

E IF IHC WB

Storage Temperature :

-20°C

Reference :

Huang, W., et al. Mol. Cell. Biol. 30(19):4575-4594(2010) Chairoungdua, A., et al. J. Cell Biol. 190(6):1079-1091(2010) Mirza, M.K., et al. J. Exp. Med. 207(8):1675-1685(2010) Guo, Q., et al. Acta Biochim. Biophys. Sin. (Shanghai) 42(7):450-456(2010) Teng, Y., et al. Zhonghua Yi Xue Za Zhi 90(14):988-992(2010)

Picture 1 File Name :

https://usbio-images.r.worldssl.net/prodimages/15/034332_1.jpg